Toksisitas Daun Mint (Mentha arvensis) Terhadap Larva Udang (Artemia salina Leach)

Authors

  • Arien Puspa Retno Akademi Farmasi Surabaya
  • Surahmaida Akademi Farmasi Surabaya

DOI:

https://doi.org/10.55123/insologi.v1i4.716

Keywords:

Mint Leaf, Toxicity, Shrimp Larvae

Abstract

Medicinal plant are part of the flora that grows and is widespread in Indonesia, one of which is mint (Mentha arvensis). Mint plant is an aromatic herbaceous plant that is widely used for air freshener, as a food garnish, and medicine. However, few studies have tested the toxicity of mint leaves. To achieve safe treatment, many studies have been carried out in pharmacological and toxicity testing of medicinal plants. The toxicity test of these medicinal plants uses the Brine Shrimp Lethality Test (BSLT) method after 24 hours of exposure to the sample being tested. This study aimed to determine the toxicity of mint leaves (Mentha arvensis) to shrimp larvae (Artemia salina Leach). Mint leaf extract was obtained from a 24-hour maceration extraction process using 96% ethanol as a solvent. Toxicity test were carried out using the Brine Shrimp Lethality Test (BSLT) method with a concentration of 1 ppm, 2 ppm, 3 ppm, 4 ppm ad 5 ppm. The percentage of deaths of shrimp larvae was calculated and calculation of LC50 value using Probit analysis. The LC50 value was obtained 3,5223 ppm and its categorized as very toxic to shrimp larvae because LC50 < 30 ppm. It can be concluded that mint leaves (Mentha arvensis) can be used as a candidate to be developed as an anti-cancer drug.

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References

Akram, M., Uzair, M., Malik, N. S., Mahmood, A., Sarwer, N., Madni, A., & Asif, H. M. (2011). Mentha arvensis linn.: A review article. Journal of Medicinal Plant Research, 5(18), 4499–4503.

da Costa, J. G., Nascimento, E. M. do, Rodrigues, F. F., & Campos, A. (2009). Phytochemical prospection, toxicity and antimicrobial activity of Mentha arvensis (labiatae) from Northeast of Brazil . Journal of Young Pharmacists, 1(3), 210. https://doi.org/10.4103/0975-1483.57066

Gadir, S. A. (2012). Assessment of bioactivity of some Sudanese medicinal plants using brine shrimp (Artemia salina) lethality assay. Journal of Chemical and Pharmaceutical Research, 4(12), 5145–5148.

Granatum, X., Selatan, S., Banyuasin, P., & Prosedur, S. S. (2018). A. marina , R. mucronata , S. alba. 18(1), 91–103.

Joshi, S., & Karna, A. K. (2013). Analysis of Phytoconstiuents and Cytotoxic Activities of Different Parts of Ocimum sanctum. International Journal of Applied Sciences and Biotechnology, 1(3), 137–144. https://doi.org/10.3126/ijasbt.v1i3.8609

Kumala, S., & Sapitri, D. W. (2011). Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract. Indonesian Journal of Cancer Chemoprevention, 2(1), 193. https://doi.org/10.14499/indonesianjcanchemoprev2iss1pp193-197

Mardina, P., Astarina, E., & Aquarista, S. (2011). Pengaruh Kecepatan Putar Pengaduk Dan Waktu Operasi Pada Ekstraksi Tannin Dari Mahkota Dewa. Jurnal Kimia, 5(2), 125–132.

Naidu, J. R., Ismail, R., & Sasidharan, S. (2014). Acute oral toxicity and brine shrimp lethality of methanol extract of Mentha spicata L (Lamiaceae). Tropical Journal of Pharmaceutical Research, 13(1), 101–107. https://doi.org/10.4314/tjpr.v13i1.15

Ntungwe N, E., Domínguez-Martín, E. M., Roberto, A., Tavares, J., Isca, V. M. S., Pereira, P., Cebola, M.-J., & Rijo, P. (2020). Artemia species: An Important Tool to Screen General Toxicity Samples. Current Pharmaceutical Design, 26(24), 2892–2908. https://doi.org/10.2174/1381612826666200406083035

R. Hamidi, M., Jovanova, B., & Kadifkova Panovska, T. (2014). Toxicological evaluation of the plant products using Brine Shrimp (Artemia salina L.) model. Macedonian Pharmaceutical Bulletin, 60(01), 9–18. https://doi.org/10.33320/maced.pharm.bull.2014.60.01.002

Saleem, M. N., & Idris, M. (2016). Podina (Mentha arvensis): Transformation from Food Additive to Multifunctional Medicine. ARC Journal of Pharmaceutical Sciences, 2(2), 6–15. https://doi.org/10.20431/2455-1538.0202002

Yousuf, T., Akter, R., Ahmed, J., Mazumdar, S., Talukder, D., Nandi, N. C., & Nurulamin, M. (2021). Evaluation of acute oral toxicity, cytotoxicity, antidepressant and antioxidant activities of Japanese mint (Mentha arvensis L.) oil. Phytomedicine Plus, 1(4), 100140. https://doi.org/10.1016/j.phyplu.2021.100140

F. Haswan, “Perancangan Sistem Informasi Pendataan Penduduk Kelurahan Sungai Jering Berbasis Web Dengan Object Oriented Programming,” J. Teknol. Dan Open Source, vol. 1, no. 2, pp. 92–100, 2018, doi: 10.36378/jtos.v1i2.23.

B. Web and D. I. Kelurahan, “3 1,2,3,” vol. 3, no. 2, pp. 342–348, 2021.

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Published

2022-08-29

How to Cite

Arien Puspa Retno, & Surahmaida. (2022). Toksisitas Daun Mint (Mentha arvensis) Terhadap Larva Udang (Artemia salina Leach). INSOLOGI: Jurnal Sains Dan Teknologi, 1(4), 385–392. https://doi.org/10.55123/insologi.v1i4.716