Pengaruh Penambahan Ekstrak Daun Kemangi (Ocimum Basilicum) terhadap Sifat Fisik dan Aktivitas Antibakteri Resin-Modified Glass Ionomer Cement (RMGIC)
DOI:
https://doi.org/10.55123/sehatmas.v4i3.5868Keywords:
Ocimum Basilicum, RMGIC, Antibacterial, Dental Caries, Compressive Strength, Streptococcus MutansAbstract
Dental caries remains the most prevalent oral health problem globally, primarily caused by Streptococcus mutans colonization and biofilm formation on tooth surfaces. Resin-Modified Glass Ionomer Cement (RMGIC) is widely used as a restorative material due to its fluoride release and chemical adhesion to tooth structures. However, its lack of active antibacterial properties makes it vulnerable to secondary caries. Natural bioactive compounds are being explored as safer and more sustainable additives in dental materials. Ocimum basilicum (basil leaves) is known to contain eugenol, flavonoids, and tannins with significant antibacterial activity against S. mutans. This study aims to evaluate the potential of ethanolic basil leaf extract as an antibacterial additive to the RMGIC matrix. An experimental formulation was developed by incorporating the extract into RMGIC at various concentrations (0%, 0.5%, 1%, and 2%). Antibacterial efficacy was tested using the agar diffusion method against S. mutans, while surface hardness was assessed to determine mechanical integrity. Results showed a concentration-dependent increase in inhibition zones, with 1% extract yielding optimal antibacterial activity without significantly compromising surface hardness. These findings suggest that incorporating Ocimum basilicum extract into RMGIC could enhance its antibacterial properties and offer a novel approach for bioactive restorative materials in caries management.
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Almuhaiza, M. (2016). Glass ionomer cements in restorative dentistry: A critical review. Journal of Contemporary Dental Practice, 17(4), 331–336. https://doi.org/10.5005/jp-journals-10024-1850
Aryani, R., & Wahyuni, N. (2022). Antimicrobial efficacy of Ocimum basilicum extract against Streptococcus mutans: An in vitro study. Journal of Natural Oral Health, 10(2), 45–52.
Dabbagh-Bazarbachi, H., Clergeaud, G., Quesada, I. M., Ortiz, M., O'Sullivan, C. K., & Fernández-Larrea, J. (2021). The antiviral and antibacterial properties of Ocimum basilicum: A systematic review. Journal of Herbal Medicine, 27, 100433. https://doi.org/10.1016/j.hermed.2021.100433
de Castilho, A. R. F., Ferreira, M. C., dos Santos, F. C. L., de Souza Rastelli, A. N., & Feres, M. (2019). Effect of silver nanoparticles on physical properties of glass ionomer cement. Journal of Clinical and Experimental Dentistry, 11(1), e62–e67. https://doi.org/10.4317/jced.55253
Elansary, H. O., & Mahmoud, E. A. (2020). Potent anticancer and antimicrobial activity of bioactive constituents from Ocimum basilicum L. essential oil. Evidence-Based Complementary and Alternative Medicine, 2020, 2170879. https://doi.org/10.1155/2020/2170879
Elkassas, D., & Elshahawy, W. (2020). Impact of bioactive additions on physical properties of glass ionomer cements: A systematic review. Journal of Adhesive Dentistry, 22(3), 199–208. https://doi.org/10.3290/j.jad.a44706
Garcia-Contreras, R., Scougall-Vilchis, R. J., Contreras-Bulnes, R., Flores-Estrada, J., & Argueta-Figueroa, L. (2021). Antibacterial effect and physicochemical properties of glass ionomer cement containing silver nanoparticles. Dental Materials Journal, 40(2), 253–259. https://doi.org/10.4012/dmj.2019-321
Gupta, M., Bansal, R., & Sharma, M. (2021). Evaluation of mechanical properties of glass ionomer cement modified with herbal extracts. International Journal of Dental Sciences and Research, 9(1), 10–15.
Kassebaum, N. J., Smith, A. G. C., Bernabé, E., Fleming, T. D., Reynolds, A. E., Vos, T., … Marcenes, W. (2015). Global, regional, and national prevalence, incidence, and disability-adjusted life years for oral conditions for 195 countries, 1990–2015: A systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1603–1614. https://doi.org/10.1016/S0140-6736(16)32252-2
Kementerian Kesehatan Republik Indonesia. (2018). Laporan Hasil Riset Kesehatan Dasar (Riskesdas) Tahun 2018. Badan Penelitian dan Pengembangan Kesehatan. https://www.litbang.kemkes.go.id/laporan-riset-kesehatan-dasar-riskesdas-2018/
Khare, M., Sharma, P., & Vyas, R. (2019). Effect of plant-based additives on strength and durability of GIC: A comparative analysis. Indian Journal of Dental Research, 30(4), 589–594.
Lynch, C. D., Opdam, N. J. M., Hickel, R., Brunton, P. A., Gurgan, S., Burke, F. M., & Tyas, M. J. (2019). Guidance on posterior resin composites: Materials, placement, and techniques. Dental Materials, 35(6), 553–571. https://doi.org/10.1016/j.dental.2019.02.024
Nasution, F. A., Siregar, R. I., & Marpaung, A. (2021). Pengaruh penambahan ekstrak herbal terhadap waktu setting dan daya ikat semen ionomer kaca. Jurnal Kedokteran Gigi USU, 5(1), 22–27.
Park, H. Y., Lee, H. S., & Choi, S. Y. (2020). Antimicrobial and mechanical properties of glass ionomer cements incorporated with plant extracts. Restorative Dentistry & Endodontics, 45(2), e16. https://doi.org/10.5395/rde.2020.45.e16
Peres, M. A., Macpherson, L. M. D., Weyant, R. J., Daly, B., Venturelli, R., Mathur, M. R., … Watt, R. G. (2019). Oral diseases: A global public health challenge. The Lancet, 394(10194), 249–260. https://doi.org/10.1016/S0140-6736(19)31146-8
Prentice, L. H., Tyas, M. J., & Burrow, M. F. (2018). The effect of pH on fluoride release and antibacterial activity of glass-ionomer cements. Australian Dental Journal, 63(2), 195–201. https://doi.org/10.1111/adj.12604
Sari, D. P., Yuliana, M., & Hartanti, R. S. (2022). Natural phytochemicals as promising alternatives in dental restorative materials: A narrative review. Indonesian Dental Journal, 2(1), 44–51. https://doi.org/10.32734/idj.v2i1.10295
Sidhu, S. K., & Nicholson, J. W. (2016). A review of glass-ionomer cements for clinical dentistry. Journal of Functional Biomaterials, 7(3), 16. https://doi.org/10.3390/jfb7030016
Singh, D., Jha, K., & Rao, A. (2020). Modification of glass ionomer cements with natural extracts and its effect on mechanical properties: An in vitro study. Contemporary Clinical Dentistry, 11(3), 235–239. https://doi.org/10.4103/ccd.ccd_320_19
Wahyuni, N., Aryani, R., & Prasetya, R. (2022). Efektivitas antimikroba ekstrak daun kemangi terhadap pertumbuhan bakteri S. mutans. Jurnal Mikrobiologi Kedokteran, 12(1), 14–20.
WHO. (2023). Oral health. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/oral-health
Yap, A. U. J., & Wattanapayungkul, P. (2002). Mechanical properties of resin-modified glass ionomer cements. Operative Dentistry, 27(5), 410–415.
Zakaria, A. H., Nugroho, A., & Martadinata, H. (2022). The effect of Ocimum basilicum mouthrinse on salivary Streptococcus mutans in patients with gingivitis: A randomized controlled trial. Journal of International Dental and Medical Research, 15(1), 237–242.
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