Optimalisasi Gut-Skin Axis melalui Edukasi Prebiotik Alami Berbasis Pangan Lokal sebagai Nutrisi Preventif Dermatitis Atopik Bagi Lansia
DOI:
https://doi.org/10.55123/abdikan.v5i3.8516Kata Kunci:
Atopic Dermatitis, Elderly, Gut-Skin Axis, Inulin, Local FoodAbstrak
The aging process physiologically triggers a decline in skin barrier function and gut microbiota dysbiosis in the elderly, which clinically manifests as xerosis cutis, senile pruritus, and the exacerbation of elderly atopic dermatitis. Prolonged reliance on topical steroid therapies poses a high risk of skin atrophy, necessitating an inside-out intervention through the optimization of the gut-skin axis. This community service activity aims to enhance the health literacy of the elderly and their family caregivers regarding the utilization of inulin-rich natural prebiotics from local functional foods as an anti-inflammatory preventive nutrition. The partner for this program is the elderly community at the Muhammadiyah Jatimulyo 1, Lowokwaru, Malang City, with a sample size of 22 participants. The implementation method was comprehensively carried out through four systematic stages: program socialization, interactive education on atopic dermatitis and prebiotic local food sources, distribution of visual media (posters and pocketbooks), and cognitive evaluation using pre-test and post-test questionnaires. The outreach successfully resulted in a significant increase in participants' knowledge concerning atopic dermatitis and natural prebiotic food sources. Through this prebiotic functional diet modification approach, a paradigm shift from curative-symptomatic care to preventive measures is expected, thereby substantially reducing the severity index of atopic dermatitis, alleviating chronic pruritus, and sustainably improving the quality of life among the elderly.
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Chen, J., Zhao, K.-N., & Vitetta, L. (2024). Short-chain fatty acids as immune modulators in inflammatory skin conditions: A review. Frontiers in Immunology, 15, Article 1385165. https://doi.org/10.3389/fimmu.2024.1385165
Chu, D. K., Koplin, J. J., Ahmed, T., Islam, N., Chang, C.-L., & Lowe, A. J. (2024). How to prevent atopic dermatitis (eczema) in 2024: Theory and evidence. Journal of Allergy and Clinical Immunology: In Practice, 12(7), 1695–1704. https://doi.org/10.1016/j.jaip.2024.04.048
de Wit, L., Fenenga, C., Giammarchi, C., di Furia, L., Hutter, I., de Winter, A., & Meijering, L. (2017). Community-based initiatives improving critical health literacy: A systematic review and meta-synthesis of qualitative evidence. BMC Public Health, 18(1), 40. https://doi.org/10.1186/s12889-017-4570-7
Du, Y., Kusama, K., Hama, K., Chen, X., Tahara, Y., Kajiwara, S., Shibata, S., & Orihara, K. (2024). Protective effects of inulin on stress-recurrent inflammatory bowel disease. International Journal of Molecular Sciences, 25(5), 2494. https://doi.org/10.3390/ijms25052494
Farage, M. A., Miller, K. W., Berardesca, E., & Maibach, H. I. (2013). Clinical implications of aging skin: Cutaneous disorders in the elderly. American Journal of Clinical Dermatology, 10(2), 73–86. https://doi.org/10.2165/00128071-200910020-00001
Fluhr, J. W., Alexis, A. F., Andriessen, A., Ferero Barrios, O. L., Bjerring, P., Foley, P., Gold, M. H., Kaderbhai, H., & Zhang, C. (2024). A global perspective on the treatment and maintenance of mature skin using gentle cleansers and moisturizers. International Journal of Dermatology, 63(12), 1676–1684. https://doi.org/10.1111/ijd.17375
Fu, Y., Wang, Y., Gao, H., Li, D., Jiang, R., Ge, L., Tong, C., & Xu, K. (2022). Associations among dietary omega-3 polyunsaturated fatty acids, the gut microbiota, and intestinal immunity. Mediators of Inflammation, 2021, Article 8879227. https://doi.org/10.1155/2021/8879227
Leeman, E. J., & Loman, L. (2024). Health literacy in adult patients with atopic dermatitis: A cross-sectional study. Journal of Allergy and Clinical Immunology: Global, 3(2), 100218. https://doi.org/10.1016/j.jacig.2024.100218
Mahmud, M. R., Akter, S., Tamanna, S. K., Mazumder, L., Esti, I. Z., Banerjee, S., Akter, S., Hasan, M. R., Acharjee, M., Hossain, M. S., & Pirttilä, A. M. (2022). Impact of gut microbiome on skin health: Gut-skin axis observed through the lenses of therapeutics and skin diseases. Gut Microbes, 14(1). https://doi.org/10.1080/19490976.2022.2096995
Pachauri, A., & Sharma, S. (2025). Unravelling the gut–skin axis: The role of gut microbiota in pathogenesis and management of psoriasis. Inflammopharmacology, 33, 3671–3678. https://doi.org/10.1007/s10787-025-01813-y
S, P. (2022). Biochemical, structural and physical changes in aging human skin, and their relationship. Biogerontology, 23, 275–288. https://doi.org/10.1007/s10522-022-09959-w
Sheng, W., Ji, G., & Zhang, L. (2023). Immunomodulatory effects of inulin and its intestinal metabolites. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1224092
Vinelli, V., Biscotti, P., Martini, D., Del Bo', C., Marino, M., Meroño, T., Nikoloudaki, O., Calabrese, F. M., Turroni, S., Taverniti, V., Unión Caballero, A., Andrés-Lacueva, C., Porrini, M., & Riso, P. (2022). Effects of dietary fibers on short-chain fatty acids and gut microbiota composition in healthy adults: A systematic review. Nutrients, 14(13), 2559. https://doi.org/10.3390/nu14132559
Völzer, B., El Genedy-Kalyoncu, M., Fastner, A., Tomova-Simitchieva, T., Neumann, K., Sill, J., Balzer, K., & Kottner, J. (2023). Prevalence and associations of xerosis cutis, incontinence-associated dermatitis, skin tears, pressure ulcers, and intertrigo in aged nursing home residents: A representative prevalence study. International Journal of Nursing Studies, 141, 104472. https://doi.org/10.1016/j.ijnurstu.2023.104472
Woo, Y. R., & Kim, H. S. (2024). Interaction between the microbiota and the skin barrier in aging skin: A comprehensive review. Frontiers in Physiology, 15. https://doi.org/10.3389/fphys.2024.1322205
Wright, B. L., Masuda, M. Y., Ortiz, D. R., Dao, A., Civello, B., Pyon, G. C., Schulze, A. R., Yiannas, J. A., Rank, M. A., Kita, H., & Doyle, A. D. (2023). Allergies come clean: The role of detergents in epithelial barrier dysfunction. Current Allergy and Asthma Reports, 23, 443–451. https://doi.org/10.1007/s11882-023-01094-x
Yao, D., Gong, X., Ma, Y., Gong, T., & Wang, G. (2023). The prevalence and interventions of xerosis cutis among older adults: A systematic review and meta-analysis. Geriatric Nursing, 54, 219–228. https://doi.org/10.1016/j.gerinurse.2023.09.018
Zhao, Y., Yu, C., Zhang, J., Yao, Q., Zhu, X., & Zhou, X. (2025). The gut-skin axis: Emerging insights in understanding and treating skin diseases through gut microbiome modulation (Review). International Journal of Molecular Medicine, 56, 1–15. https://doi.org/10.3892/ijmm.2025.5651
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Hak Cipta (c) 2026 Dwi Nurwulan Pravitasari, Tara Mandiricha, Fathiyah Safitri, Nazida Febyan, Rahmad Fadilah
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